Apply

We are always happy to receive applications form enthousiastic students at all levels interested in regenerative medicine. If you would like to work with us please send your updated CV and a motivation letter to: 

  Hepatology and Cell Therapy Lab CHU Sainte-Justine Research Center – Université de Montréal 3175 Ch. Côte-Sainte-Catherine Montréal H3T 1C5, QC Canada Phone: +1-514-345-4931 ext. 4299 Fax: +1-514-345-4999 E-mail: m.paganelli@umontreal.ca        

PhD and/or Post-doc position

Principal investigator: Dr Massimiliano Paganelli

 Research interest:

Dr Paganelli is looking for students motivated to carry out cutting-edge research in his regenerative medicine-centered laboratory. Main focus of the lab is the study and treatment of liver disease using liver organoids generated from human induced pluripotent stem cells (iPSC).  Such organoids are used in the lab to understand the physiology of liver development and regeneration, as well as the pathophysiology of complex liver diseases such as fibrosis and cirrhosis or rare genetic liver conditions such as hereditary tyrosinemia. The liver organoids are also at the heart of the Encapsulated Liver Tissue, a technology capable of replacing liver functions and treating acute liver failure. Such a technology was conceived in Dr. Paganelli’s laboratory and recently licensed to a spin-off company. A summary if the research conducted by Dr Paganelli can also be found on the webpage https://www.paganellilab.org

 Several research projects focusing on liver tissue engineering are available, from the more fundamental encompassing the study of liver physiology and development and the pathophysiology of various liver diseases, to the more translational aiming at the identification and validation of new treatments for severe liver conditions affecting children and adults. Details will be discussed with applicants. The choice of a project will depend on the student skills, scientific interests, previous experience and education.

 Working environment:

The student will join a young, international and multicultural team of passionate researchers that are devoted to develop new treatments and advance the field of regenerative medicine. The lab is located at the new CHU- Sainte-Justine Research Center (https://research.chusj.org/en/Home). The hospital is affiliated to the University of Montreal and provides state of the art equipment and a vibrant scientific environment. University of Montreal is one of the leading universities in Canada (https://www.umontreal.ca/). Interaction with the pharmaceutic industry for the translation of developed technology constitutes a significant part of the activity of the laboratory, and provides future opportunities for students after their diploma. Dr. Paganelli collaborates with renowned research groups in Canada, the U.S.A., Europe and Asia. International experiences and exchanges, if required by the student, are therefore a possibility.

 Qualifications:

Dr. Paganelli is looking for highly motivated young scientists willing to fully commit to an exciting field of science. The hired student is expected to have a specific interest in regenerative medicine, attention to detail and precision, and to be a good team player. Master degree or PhD in biology, medical sciences or other relevant field is required. Experience in cellular and molecular biology and the ability of working with animal models is an asset. To obtain the position is mandatory to have an excellent academic record, since the students will be required to apply for scholarships at the main funding agencies in Canada (FRSQ, CHIR among others). The official language of the institution is French but excellent knowledge of the English language is necessary to meet the requirements of this position.

 Salary:

Salary will be provided according to the standards of the research center.

 Deadlines:

Applications for post-graduate positions are accepted at the University of Montreal by September 1st and February 1st, but dates will be defined according to the program for which the student is eligible. International students also need to consider the time needed for visa application. Interested applicants are invited to start the process as soon as possible.

 Submit your application:

Interested candidates should send the following documents to Dr Paganelli by email at:

s.selleri@umontreal.ca

 

  • Curriculum vitae
  • Transcript of notes (for the PhD position)
  • Letter of motivation
  • References (contact information of 2 persons, name, email and phone number)

 

While all candidatures will be taken in consideration, only selected students will be contacted for an interview.